Fri Jun 17 2022

37 articles - From Friday Jun 10 2022 to Friday Jun 17 2022

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Guidelines

Guidelines, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Pancreatology

Venous resection for pancreatic cancer, a safe and feasible option? A systematic review and meta-analysis.

VR is a safe and feasible option in patients with pancreatic cancer and suspicion of venous involvement, since VR during pancreatic surgery has comparable overall survival and complication rates.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Affordability influences nutritional quality of seafood consumption among income and race/ethnicity groups in the United States.

New insights into the relation between seafood affordability and consumption patterns among income and ethnicity groups suggest that specific policies and interventions may be needed to enhance the consumption of seafood by different groups.

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Birth length is the strongest predictor of linear growth status and stunting in the first 2 years of life after a preconception maternal nutrition intervention: the children of the Women First trial.

Substantial improvements in postnatal growth are likely to depend on improved intrauterine growth, especially during early pregnancy.

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Causal associations of alcohol consumption with cardiovascular diseases and all-cause mortality among Chinese.

Our analyses extend the evidence of the harmful effect of alcohol consumption to total CVD (including CHD) and all-cause mortality, highlighting the potential health benefits of lowering alcohol consumption, even among light-to-moderate male drinkers.

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Consumption of takeaway and delivery meals is associated with increased BMI and percent fat among UK Biobank participants.

Homecooked meals were more often consumed by those with low BMI and percent body fat, whereas delivery and takeaway meals were more often eaten by individuals with higher BMI. Consumption of fast-food/café meals was not consistently associated with BMI or percent body fat. The direction of causality in these associations cannot be inferred from this cross-sectional study.

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Estimating national and subnational nutrient intake distributions of global diets.

The shape of nutrient intake distributions differs based on nutrient and subgroup and strongly influences estimates of nutrient intake inadequacy. This research represents an important contribution to the availability and application of dietary intake data for diverse subpopulations around the world.

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Levels of abdominal adipose tissue and metabolic-associated fatty liver disease (MAFLD) in middle age according to average fast-food intake over the preceding 25 years: the CARDIA Study.

There were monotonic higher levels of VAT, liver fat, and odds of having MAFLD in middle age according to higher average fast-food intake over the preceding 25 y.

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Starting complementary feeding with vegetables only increases vegetable acceptance at 9 months: a randomized controlled trial.

Providing vegetables as first foods increased vegetable intake at 9 mo of age and may be an effective strategy for improving child vegetable consumption and developing preferences for vegetables in infancy.

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Tryptophan oxidation in young children with environmental enteric dysfunction classified by the lactulose rhamnose ratio.

The static plasma KTR value is not a good indicator of the dynamic Trp flux down its oxidative pathway. In a poor sanitary environment, children without EED actually have a faster Kyn synthesis rate, which might be beneficial, because of the cytoprotective and anti-inflammatory functions of downstream metabolites.

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Liver Transpl

Bile duct anastomosis does not promote bacterial contamination of autologous blood salvaged during living donor liver transplantation.

We found that bile from the newly implanted liver graft is sterile in LDLT and BDA does not increase the risk of bacterial contamination of salvaged blood, supporting the use of blood salvage during LDLT even after BDA. Leukoreduction converted al autologous blood samples positive for bacteria to negative. The clinical benefit of leukoreduction for salvaged autologous blood on post-LDLT bacteremia needs further research.

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Logistical burden of offers and allocation inefficiency in circle-based liver allocation.

Circle-based allocation is associated with increased logistical burdens that are geographically heterogeneous. Continuous distribution systems will have to be carefully designed to avoid exacerbating this problem.

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Waitlist mortality of young patients with biliary atresia: Impact of allocation policy and living donor liver transplantation.

The proportional increase in LDLT decreased the median waitlist duration of transplanted patients from 1.5 months in PRE, to 0.85 month in POST (P=0.003). Since 2014, waitlist mortality in young BA patients has strongly decreased in the ET region. Rather than associated with prioritized allocation of deceased donor organs, the decreased waitlist mortality was related to a higher proportion of patients undergoing LDLT.

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Pancreas

Aggressive Intervention of Pancrelipase After Pancreatectomy Prevents Deterioration of Postoperative Nutritional Status.

The early administration of pancrelipase after pancreatectomy improved nutritional status after pancreatectomy.

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Analysis of the Pancreatic Cancer Microbiome Using Endoscopic Ultrasound-Guided Fine-Needle Aspiration-Derived Samples.

Endoscopic ultrasound-guided fine-needle aspiration samples were valuable for PC microbiome analysis, revealing that the bacterial composition of PC is different from that of the stomach and duodenum.

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Assessing the Role of Operative Intervention in Elderly Patients With Nonfunctional Pancreatic Neuroendocrine Neoplasms.

Resection of nonfunctional PanNENs in elderly patients is associated with improved survival compared with nonoperative management. Resection could be considered in appropriate operative candidates, regardless of tumor location, but the perioperative mortality rate must be considered.

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Class III ß-Tubulin Expression Is of Value in Selecting nab-Paclitaxel and Gemcitabine as First-Line Therapy in Unresectable Pancreatic Cancer.

Class III ß-tubulin might be a predictive factor for the response of GnP, but not a prognostic factor for OS, helping the selection of an optimized first-line chemotherapy regimen for unresectable PDAC.

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Clinical Features of Pancreatic Neuroendocrine Microadenoma: A Single-Center Experience and Literature Review.

Multiple sporadic NEMAs and grade 2 NEMAs were observed, suggesting that NEMA may have malignant potential. Thus, NEMAs should be carefully monitored for lymph node metastasis and postoperative recurrence.

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Coefficient of Fat Absorption to Measure the Efficacy of Pancreatic Enzyme Replacement Therapy in People With Cystic Fibrosis: Gold Standard or Coal Standard?

Based on the evidence, we conclude that CFA as a measure of the efficacy of PERT is more of a "coal standard" than a gold standard; developing suitable alternatives should be a priority.

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Combination of Body Mass Index and Fasting Blood Glucose Improved Predictive Value of New-Onset Prediabetes or Diabetes After Acute Pancreatitis: A Retrospective Cohort Study.

Body mass index and FBG are independent predictors of NODAP. The combination of BMI and FBG can refine the prediction of NODAP and identify candidates for clinical prevention.

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Estimating Fatty Pancreas: A Preoperative Bedside Assessment by Bioelectric Impedance Analysis: Implications for Pancreatic Surgery.

Bioelectric impedance analysis represents a valid alternative to assess pancreatic steatosis.

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Pancreatic-Like Cells Derived From Mouse Embryonic Stem Cells Are Regulated by Pdx1 Involving the Notch Pathway.

Pdx1+-ESC could differentiate into pancreatic-like cells with involvement of the Notch pathway.

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Rising Prevalence of Anxiety and Depression in Chronic Pancreatitis: A Nationwide Analysis.

Anxiety and depression are increasingly recognized diagnosis in patients with CP. Careful management and treatment of psychiatric illnesses and improving quality of life need to be addressed for these patients.

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Splanchnic Vein Thrombosis: A Harbinger of Infection in Peri/Pancreatic Necrotic Collections.

Escherichia coli and Staphylococcus were the most common organisms grown from necrotic collections and blood respectively. Presence of splanchnic vein thrombosis was a significant factor for development of IPN and bacteremia on univariate as well as multivariate analysis.

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The Additional Diagnostic Benefit of Pancreatic Cancer Molecular Profiling After Germline Testing.

Tumor molecular profiling after germline testing increased the detection of actionable alterations by 5-fold. Tumor molecular profiling is a necessary complement to germline genetic testing to fully inform therapeutic decision making for al patients with pancreatic cancer.

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The Characteristics and Risk Factors of Asparaginase-Associated Pancreatitis in Pediatric Acute Lymphoblastic Leukemia.

The incidence of AAP was 4.7% in ALL patients treated with TPOG-ALL protocol. Although a higher cumulative dose of asparaginase in TPOG-ALL-2013 may attribute to the pancreatic toxicity, unidentified factors such as genetic predisposition or other drugs still need further study.

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Pancreatology

Invasive IPMN relapse later and more often in lungs in comparison to pancreatic ductal adenocarcinoma.

I-IPMN showed a different recurrence pattern compared to PDAC, with a higher lung tropism, and longer DFS. This different biological behavior is associated with lower rates of neuroinvasion and nodal involvement, especially in early-stage disease.

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Nal-IRI/5-FU/LV versus modified FOLFIRINOX and FOLFIRI as second-line chemotherapy for unresectable pancreatic cancer: A single center retrospective study.

Given the trend toward longer OS in the mFFX group and the lower incidence of adverse events in the FOLFIRI group, both mFFX and FOLFIRI, as well as nal-IRI/5-FU/LV, can be treatment options for second-line chemotherapy for unresectable pancreatic cancer.

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Routine prophylactic abdominal drainage versus no-drain strategy after distal pancreatectomy: A multicenter propensity score matched analysis.

In this international retrospective multicenter study, a selective no-drain strategy after DP was not associated with higher rates major morbidity or radiological interventions as compared to routine prophylactic abdominal drainage. Although the rate of POPF was lower in the no-drain group, randomized trials should confirm the safety and outcome of a no-drain strategy after DP.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Liver Transpl

Comparing Preservation Solutions for Static Cold Storage in DCD Liver Transplantation.

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Pancreatology

An ethical analysis of endoscopic therapy decision-making in patients with refractory substance use disorder and chronic pancreatitis.

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Letters&Replies

Letters to the editors and authors’ replies


Others

all remaining publications eg case reports, images of the month, etc…

Am J Clin Nutr

Does excessive fast-food consumption impair our health?

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Healthy eating for healthy aging: What and when to eat as an older adult.

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Making every bite count: best practices for introducing foods during the complementary feeding period.

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Starting life right: birth length matters.

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The need for nuance with dietary data.

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Liver Transpl

Domino Liver Transplantation: expanding the liver donor pool to the pediatric recipient.

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Pancreas

Poorly Differentiated and Undifferentiated Pancreatic Neuroendocrine Carcinoma Management and Outcomes: A Surveillance, Epidemiology and End Results Assessment.

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